NEONATAL DISRUPTION OF SERINE RACEMASE CAUSES SCHIZOPHRENIA-LIKE BEHAVIORAL ABNORMALITIES IN ADULTHOOD: CLINICAL RESCUE BY D-SERINE.

Neonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serine.

BackgroundD-Serine, an endogenous co-agonist of the N-methyl-D-aspartate (NMDA) receptor, is synthesized from L-serine by serine racemase (SRR).Given the role of D-serine in both neurodevelopment and the pathophysiology of schizophrenia, we examined whether neonatal disruption of D-serine synthesis by SRR inhibition could induce behavioral abnormal

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Effects of a sustained-release multi-trace element ruminal bolus on sex ratio, reproductive traits and lambs growth in synchronized Afshari ewes

The objective of the present study was to investigate the effects of a sustained-release multi-trace element ruminal bolus on sex ratio, the reproductive performance and lambs growth of Afshari ewes.Eighty Afshari cycling ewes during breeding season were used in the essie well nested energy trial.The animals were synchronized using CIDR for 14 days

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Mindfulness-based stress reduction training supplemented with physiological signals from smartwatch improves mindfulness and reduces stress, but not anxiety and depression.

IntroductionMindfulness-Based Stress Reduction (MBSR) helps counteract the negative consequences of stress.An essential aspect of mind-body therapies is learning to be mindful of emotional reactions and bodily sensations, a process defined as interoceptive awareness.This awareness can also be enhanced by providing physiological feedback from a smar

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